Immunology

Understanding the link between immunology and respiratory health is critical in understanding many lung diseases. 

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$973,894
total amount funded

21
# of projects funded

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All Projects 

Applicant Title Institution Province Amount Awarded
Ensminger, Alexander Defining the host – pathogen interface in TNF-alpha depleted cells. University of Toronto Ontario $50,000
Gill, Sean TIMP3 Regulates Macrophage Function Following Lung Injury University of Western Ontario Ontario $50,000
LeFoll, Bernard Exploring the effects of prazosin on nicotine-induced dopamine release in humans: A [11C]-PHENO PET study Centre for Addiction and Mental Health Ontario $50,000
Granville, David Extracellular Granzyme B and Pulmonary Epithelial Barrier Disruption UBC Pathology and Laboratory Medicine British Columbia $50,000
Shafa, Medhi Functional repair of surfactant protein B deficiency in patient-derived induced pluripotent stem cells using the TALEN and CRISPR/Cas9 Ottawa Hospital Research Institute (OHRI) Ontario $90,000
Marr, Nico Immunological determinants of severe respiratory syncytial virus infection in early life Dalhousie University Nova Scotia $50,000
Kelly, Margaret Neutrophil-Mast Cell Interactions in the Pathogenesis of Hypersensitivity Pneumonitis University of Calgary Alberta $30,000
Wootton, Sarah Nuclease-based Gene Targeting for Correction of Alpha-1-antitrypsin Deficiency University of Guelph Ontario $49,923
Wootton, Sarah Nuclease-based gene targeting for correction of alpha-1-antitrypsin deficiency University of Guelph Ontario $48,116
Palaniyar, Nades Lung proteins as serum biomarkers for Bronchiolitis Obliterans Syndrome (BOS) in patients receiving stem cell therapy Hospital for Sick Children/University of Toronto Ontario $41,418
Thébaud, Bernard Patient-derived induced pluripotent stem cells for the correction of surfactant protein B deficiency Ottawa Hospital Research Institute Ontario $48,421
Gill, Sean Pulmonary Microvascular Endothelial Cell Activation during Lung Injury is Regulated by TIMP3 University of Western Ontario Ontario $49,991
Labiris, N. Renee Pulmonary microvascular endothelial cell dysfunction during sepsis is mediated by TIMP3 McMaster University Ontario $49,707
Marr, Nico Role of RIG-I in susceptibility of infants to severe RSV infection University of British Columbia British Columbia $60,000
Hirota, Jeremy The airway epithelium NLRP3 inflammasome: Central player in air pollution mediated innate and adaptive immune responses. University of British Columbia British Columbia $43,400
Thébaud, Bernard Site-specific genetic correction of surfactant protein B deficiency in patient-derived induced pluripotent stem cells Ottawa Hospital Research Institute (OHRI) Ontario $41,418
Hirota, Jeremy The role of uric acid in airway health and disease UBC Department of Medicine – VCHRI British Columbia $50,000
Gill, Sean TIMP3 Regulates Marcophage Function Following Acute Lung Injury The University of Western Ontario Ontario $50,000
Marchant, David Elucidating the Transmission Dynamics of Respiratory Syncytial Virus in the Community by Correlation of Whole Genome Sequencing and Virulence Determination of Samples from Infected Patients in Northern Alberta University of Alberta Alberta $30,000
Jamieson, Kyla The effects of combined bacterial and rhinovirus exposure on human bronchial epithelial proinflammatory and host defense responses University of Calgary Alberta $11,500
Lacy, Paige Cytokine trafficking and secretion in eosinophils University of Alberta Alberta $30,000